Analysis
U.S CDC Expert Panel: mRNA COVID-19 Vaccines Linked To An Elevated Risk Of Heart Inflammation Issues In Adolescents And Young Adults
- CDC expert panel note ‘likely association’ between Covid-19 vaccines and rare heart condition in young people.
- Immunization Safety Office at the CDC, said the agency has so far received reports of 1,226 cases of myocarditis, with 827 (67.5%) reported after dose two of either the Moderna or Pfizer vaccine.
- The cases are mostly concentrated on younger groups, particularly men under 30, having higher rates of myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining around the heart) following vaccination
Pfizer vaccine challenges for India.
A panel comprising of expert advisors to the Centers for Disease Control and Prevention (CDC) has acknowledged that there was a “likely association” between mRNA Covid-19 vaccines and an elevated risk of heart issues in adolescents and young adults, Statnews reported.
"Clinical presentation of myocarditis cases following vaccination has been distinct, occurring most often within 1 week after dose two, with chest pain as the most common presentation, " said Grace Lee, MD, chair of safety subcommittee of Advisory Committee on Immunization Practices (ACIP) that advices CDC.
"mRNA vaccines may be a new trigger for myocarditis, yet it does have some different characteristics," said Matthew Oster, MD, MPH, from the CDC's COVID-19 Vaccine Task Force.
The most common symptoms reported by patients were chest pain, shortness of breath, and difficulty sleeping.
Based on evidence, the cases were mostly concentrated on younger groups, particularly men under 30, having higher rates of myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining around the heart) following vaccination with the shots from Moderna or Pfizer-BioNTech. Most cases have occurred soon after the second shot of the two-dose regimens.
Immunization Safety Office at the CDC, said the agency has so far received reports of 1,226 cases of myocarditis, with 827 (67.5%) reported after dose two of either the Moderna or Pfizer vaccine.
Of those cases identified after second doses, 563 followed the Pfizer vaccine series. In total, that's approximately 12.6 heart inflammation cases per million doses administered in the United States.
Among the 1,226 patients, 484 are younger than 29, and roughly two-thirds are men.
The myocarditis and pericarditis associated with vaccines are usually mild and respond well to a course of treatment with non-steroidal anti-inflammatories.
Officials said they are planning to add warnings about myocarditis and details about symptoms to Covid-19 vaccine fact sheets provided to administrators of the shots and people who get them
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