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Covid-19: Trials Of Anti-Leprosy Mw Vaccine To Be Conducted On 40 Patients In Three Hospitals, Says PGIMER Director
Swarajya Staff
May 03, 2020, 04:56 PM | Updated 04:56 PM IST
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The Director of PGIMER, Chandigarh has informed on Sunday (3 May) that the safety trial of anti-leprosy drug Mycobacterial w (Mw) drug has been completed and its actual trials would be held at PGI-Chandigarh, AIIMS-Delhi and AIIMS-Bhopal, reports ANI.
Mycobacterium indicus pranni, which was earlier known as Mw is a non-pathogenic mycobacterial species. Based on its metabolic properties and growth characteristics, it is classified as a member of the Mycobacterium avium complex.
In India, the immune-boosting drug was developed in 1966 as an anti-leprosy drug which resulted in a successful treatment to cure leprosy. It acts through the toll-like receptor pathway and enhances host-T cell responses.
Earlier, Council of Scientific and Industrial Research (CSIR) had started the clinical trial on an anti-leprosy vaccine to identify if it can be used as a COVID-19 vaccine.
In a recently concluded multi-center trial of the drug, it had been found that Mw reduces mortality in ICU patients with severe sepsis. A PGI spokesperson reportedly said, "Mw can potentially decrease the cytokine storm seen in patients with Covid-19 and may thus be of potential benefit in managing these patients and decreasing mortality."
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